Trouble codes P2006 P0300

So last night i was driving home and my car stumbled and the next thing i know i feel like i a, driving on three cylinders and my CEL is blinking. The car starts to run find and the CEL is solid, I got the codes pulled and I got a P2006 runner stuck closed and a P0300 random cylinder misfire. I understand the codes what I am wonder is with the runner stuck closed could it be causing the P0300 code to come up and my car to hesitate when I am accelerating and with what happened last night. Any help would be cool, my car has 123,XXX on it.
 

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