Mainly just looks. I've heard that a longer E-string on the top side of the nut gives a different tone. I'm not sure I believe it. I've played Chris' Carvins that are both regular and reverse, as well as the 3x3 setup, and I can't tell any difference (unplugged). I can't say it makes a difference plugged in because each has different pickups.
I'm a huge fan of the Karloff Mummy guitar.
I'm a huge fan of the Karloff Mummy guitar.