2009 CX-9 Touring AWD has a mild higher pitched whine when hitting the gas between 40-55 mph. Using the manual shifter, I can attest that in 5th there is no whine and it also doesn't do it at higher speeds in 6th.
some suspects to look at :
1) bad wheel bearing
2) PTU (transfer case) leaking
http://www.mazdas247.com/forum/showthread.php?123847373-Changing-CX-9-transfer-case-gear-oil-%28photos%29
3) need to drain and fill transmission oil