Well there are some similarities between this and other movies. Yes it was a take on Romeo and Juliet. That is like a major given. As far as Blade. Well there are a lot of differences. And there are some similarities. If you get into the whole lore thing, it is a very new take. If you get into the whole nowaday thing...then yes it is like White Wolf/Blade/Any other vamp movie that believes in Masquerade.
Having the weapons to fight each other is very Blade and very not, other series have used it too.
It is unlike Blade with the whole invincibility issue. Other than the werewolf/vamp being. But you don't know if he is invincible or just stronger then the rest. Blade is more of a one man fighting machine. Selene is actually fearful of getting her head ripped off by the werewolves. Blade was indifferent to any enemy. He was never fearful, not even once!
The new stuff is having a vampire Ancient sleep until their next reign, the origin of vampire/werewolf, and the fact that a vamp could get knocked up.
There are lots of wholes in the story. I don't claim it is so original or anything of the sort. But come on, how many things are truly original???
Even R.E. is just a hop skip and jump from Night of the Living Dead.
Oh, and the trailor for that.....I totally thought it was another commercial. I was getting sooooo pissed off at that! 10 commercial. I swear 10!!! And then to think I was going to see another one....and then it was RE 2....yeah it got me good!