a big issue we will run into is the actual fuel volume entering the combustion chamber. With direct injection, there is basically no time (0.04s at 2000rpm, 0.005s at 6000rpm) for the fuel to mix with air. This is the fundamental reasion why our cars are running rich already...
There is just going to be a physical limitation to the whole direct injection thing that will hold us back. Is it 300hp? 350? 400? Doesnt matter how much pressure you put behind it (and I dont believe there are many aftermarket DI injectors on the market), at one point the engine just wont be able to mix enough air in to get a full burn. Its more then just the fuel system though. The angle of the injector, the heads, valve locations, and even the piston shape play a major role in this.
Unfortunitly, its going to take trial and error to find out for sure.