Is it possible? Yes. Have I thought about doing it? Yes. lol
Realistically on a DD you're going to have some really high cruising BAT's which could lead to tip in and part throttle issues unless you're running E85. You'll be limited to what you can do but it would be great for autocross and drag strip runs. As long as you have a way to cool down the car in between those runs.
Personally, I just don't like the idea of 200* temps until the meth hits. No you could combat this by spraying a small amount of meth during cruise like the diesels do to boost MPG's but I'm still not a huge fan.
On the other hand. I do think this could be promising for the 300-350hp range....
http://www.frozenboost.com/product_...d=220&osCsid=7c4c7c65467c3813de111099efebbbba
That combined with D01 pre-turbo meth nozzle and a somewhat sizeable jet (D07-D10 depending on power goals) on the intercooler end tank would probably be ideal and could push that to 400+hp though the intercooler would be a restriction at that power level.