Well, no, any engine, including an RC engine, less air for a given amount of fuel richens the mixture. When you adjust the needle valve on an R/C engine to reduce the amount of fuel bleeding into the cylinder, you are leaning out the mixture, increasing power (to a point), increasing heat, and decreasing lubrication, eventually leading to the piston becoming one with the cylinder liner.
If you open that needle up - and you've probably done this with the motor running, the whine of the engine gets lower pitched, and it won't rev as high. As you keep opening it up and making it richer, the engine starts to choke a little, running rougher, and in the case of a nitro engine, spitting castor/synth oil all over the damn place.
All of this is exactly the same in the car. The only difference is that instead of spitting oil out all over the lexan, unburned and partially burned hydrocarbons collect on our tailpipes.