Thule Ascent 1100 and Thule Sidearm bike roof rack
My 2 cents...
I've got the Thule Ascent 1100 and the Sidearm bike roof rack mounted on the standard OEM Mazda roof racks.
Inteference with doors, antenna, etc. - none whatsoever, and I have the cargo carrier mounted as far to the rear as it will go.
Width-wise, if you're looking to mount both a bike rack and cargo carrier on the OEM roof racks, 25-26" is about as wide a cargo carrier as you can get and still comfortably have space to mount a roof-mounted bike rack.
Moonroof, I can definitely open it without problems with the cargo carrier alone. With the bike rack on, I need to remember to use the smallest length bolts on the front roof rack or I'll hit the bike rack fastening nuts.
Noise-wise, I have no moonroof wind deflector. With the OEM roof racks mounted alone, interior cabin noise is not a big deal, especially with the plastic noise-reduction clips mounted on the racks. With the cargo carrier, I've noticed a fair amount of noise past 100km/h and definitely with cross-winds. With the bike rack and the cargo carrier together, the noise is noticeably louder, and conversation is impossible with the moonroof open at typical highway speed limits (100 km/h, around 65 miles/h). I hardly ever open the moonroof with both the bike rack and cargo carrier on together, and I tend to keep the moonroof "shade" closed as that helps deaden the noise.
Capacity wise, best way I have of visualizing the space available with the Ascent 1100 is that it can carry 4 filled expedition-sized hiking backpacks (80L capacity) with some room left over in the ends for boots and small bags. Main limitation is that the bulky stuff needs to go in the middle, due to the low height of the cargo carrier.
Without any bikes mounted on the roof, I can probably get through 80-90% of parking garages with low roof clearances with the Ascent 1100 and OEM racks, but just barely (with an inch or two to spare). If you've got at least 7' 6" of clerance, you're OK with the Ascent 1100 and OEM rack.